Samaneh Rashtbari, Gholamreza Dehghan*, Reza Yekta, Abolghasem Jouyban
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Mohammad Reza Asgharzadeh, Mohammad M. Pourseif, Jaleh Barar , Morteza Eskandani, Mojtaba Jafari Niya, Mohammad Reza Mashayekhi, Yadollah Omidi*
Increased expression of TSGA10 associated with the reduced metastasis in the MDA-MB-231 cells. TSGA10 showed interaction with HIF-1α with high affinity. TSGA10 expression is altered under the hypoxia, indicating its potential as a bio-target for cancer therapy.
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Mohammad Mostafa Pourseif, Mitra Yousefpour*, Mohammad Aminianfar, Gholamali Moghaddam, Ahmad Nematollahi
The minigene vaccine construct is designed based on the B and T cell epitopes of E. granulosus enolase protein, and ligands for TLR-2 and TLR-4. The minigene vaccine showed stable properties for proper binding with the Toll-like receptors.
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Khalil EL Khatabi , Ilham Aanouz, Marwa Alaqarbeh, Mohammed Aziz Ajana, Tahar Lakhlifi, Mohammed Bouachrine*
Molecular docking was performed to explore the binding affinity of the 12 selected molecules in the target enzyme and then evaluated for in silico ADMET properties. The best hits were subjected to molecular dynamics simulation.
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Raja Rajeswari Rajeshkumar , Banoth Karan Kumar , Pavadai Parasuraman , Theivendren Panneerselvam , Krishnan Sundar , Damodar Nayak Ammunje , Sureshbabu Ram Kumar Pandian , Sankaranarayanan Murugesan , Shanmugampillai Jeyarajaguru Kabilan , Selvaraj Kunjiappan*
The bioactive compounds from Cynodon dactylon potentially degrade the α-Syn aggregation in the brain through in silico molecular docking investigations. A molecular dynamics simulation confirms the stability of the α-Syn-ligand complex.
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Ali Zeiz , Ranin Kawtharani, Mirvat Elmasri, Ghada Khawaja, Eva Hamade, Aida Habib, Abeer J. Ayoub, Mohamed Abarbri, Mohammad H. El-Dakdouki*
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Muammar Fawwaz* , Kenji Mishiro* , Arwansyah Arwansyah, Ryuichi Nishii, Kazuma Ogawa*
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Navid Mohammadjani , Sahand Karimi, Musa Moetasam Zorab , Morahem Ashengroph* , Mehran Alavi*
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Chaithra R Shetty , C. S. Shastry* , Parasuraman P, Srinivas Hebbar
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Sara Shamsian , Babak Sokouti, Siavoush Dastmalchi*
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